Aldehyde Dehydrogenases
Can We Change the Rate-Limiting Step of an Aldehyde Dehydrogenase?, by Henry Weiner and Kwok Ki Ho
Unexpected Encounters in Simulations of the ALDH Mechanism, by John Hempel, Hugh B. Nicholas Jr., Shawn T. Brown, and Troy Wymore
Inhibitory Effects of Disulfiram and Its Metabolites on Pseudomonas aeruginosa Betaine Aldehyde Dehydrogenase and Growth, by Víctor J. Zaldívar-Machorro, Patricia Demare, María R. Ramírez, Ignacio Regla, and Rosario A. Muñoz-Clares
Reversible Inactivation of Mitochondrial Aldehyde Dehydrogenase through Post-Translational Modifications in Hepatoma Cells and Alcohol-Fed Rat Livers, by Kwan-Hoon Moon, Bong-Jo Kim, Jie Wan, Young-Mi Lee, Mohamed A. Abdelmegeed, and Byoung-Joon Song
Inhibition of Mitochondrial Aldehyde Dehydrogenase-Mediated Oxidation of 3,4-Dihydroxyphenylacetaldehyde, by Virginia R. Florang, Jennifer N. Rees, Nicole K. Brogden, David G. Anderson, and Jonathan A. Doorn
Trans-4-hydroxy-2-nonenal (HNE), a Biochemical Tool (…as Well as a Toxin), by Jiri Brichac, Ales Honzatko, Laura Leiphon, and Matthew J. Picklo
Detoxification of Chloroacetaldehyde by Human Class-9 Aldehyde Dehydrogenase (ALDH9A1), by Mohammad Salad, Rainer Grant, Alexander Reberg, and Lakshmaiah Sreerama
Identification of Polymorphic Human Class-3 Aldehyde Dehydrogenases, by Lakshmaiah Sreerama, Rainer Grant, Bari Revee, Aaron Gross, and Daniel D. Gregory
Phylogenetic and Structural Relationships of the Betaine Aldehyde Dehydrogenases, by Adriana Julián-Sánchez, Héctor Riveros-Rosas, León P. Martínez-Castilla, Roberto Velasco-García, and Rosario A. Muñoz-Clares
Ionic Strength Dependency of Urea Effect on Renal Betaine Aldehyde Dehydrogenase Stability, by Hector G. Ayala-Castro and Elisa M. Valenzuela-Soto
Effects of Monovalent Cations on the Structure and Thermal Stability of Betaine Aldehyde Dehydrogenase from Pseudomonas aeruginosa, by Georgina Garza-Ramos, Ernesto Carrillo-Nava, Miguel Costas, Carlos Mújica-Jiménez, Roberto Velasco-García, and Rosario A. Muñoz-Clares
ALDH3A1 Expression Is Modulated by Docosahexaenoic Acid through Peroxisome Proliferator-Activated Receptors (PPARs) in Human Lung Adenocarcinoma Cells, by R. A. Canuto, M. Maggiora, G. Martinasso, M. Oraldi, V. Vasiliou, A. Trombetta, and G. Muzio
The “Asian” Variant Equivalent of Yeast Aldehyde Dehydrogenase Can Inactivate the Active Yeast Enzyme in vivo: A Knock-in Type Experiment Using Yeast to Mimic Liver Cells, by Abhijit Mukhopadhyay, Bao-Xian Wei, and Henry Weiner
A Hepatocyte Inflammation Model for Carbonyl Induced Liver Injury: Drugs, Diabetes, Solvents, Chlorination, by Peter J. O’Brien, Shahrzad Tafazoli, Katie Chan, Mariam Mashregi, Rhea Mehta, and Nandita Shangari
Therapeutic Intracellular Targets for Preventing Carbonyl Cell Death with B Vitamins or Drugs, by Rhea Mehta and Peter J. O’Brien
Alcohol Dehydrogenases
Recombinant Mouse Alcohol Dehydrogenase 1: Kinetic Mechanism, Substrate Specificity and Oxidation of 20-Hydroxyeicosatetraenoic Acid, by Bryce V. Plapp, Hirekodathakallu V. Thulasiram, Kristine B. Berst, and Terry L. Kaduce
Functional Roles of Alcohol Dehydrogenases in Human Ethanol Metabolism, by Shih-Jiun Yin, Shou-Lun Lee, Chung-Tay Yao, and Ching-Long Lai
Kinetic Analysis of SDRs, ADHs and AKRs toward Free and CRBPI-bound Retinoids: Effect of Tween-80 and Microsomal Membranes, by Oriol Gallego, Olga V. Belyaeva, Sergio Porté, F. Xavier Ruiz, Anton V. Stetsenko, Elena V. Shabrova, Natalia V. Kostereva, Sílvia Martras, Xavier Parés, Natalia Y. Kedishvili, and Jaume Farrés
Structural and Functional Features of Cinnamyl Alcohol Dehydrogenase (Adh6p) from Saccharomyces cerevisiae, by Carolina Larroy, Eva Valencia, Ignacio Fita, Xavier Parés, and Josep A. Biosca
Diversity of Beta-Hydroxyacid Dehydrogenases in Plants, by John W. Hawes
Carbonyl Reductases
Multifunctional Carbonyl Reductases of the Short-Chain Dehydrogenase/Reductase (SDR) Superfamily in Mammalian Species, by Edmund Maser and Frank Hoffmann
The Aldo-Keto Reductase Superfamily Homepage: 2006 Update, by Jason E. Drury, David Hyndman, Yi Jin, and Trevor M. Penning
Life without Aldose Reductase, by Satish K. Srivastava, Kota V. Ramana, and Aruni Bhatnagar
Species Comparison of AKR7A Family Members, by Elizabeth M. Ellis
Retinoid-Active Short-Chain Dehydrogenases/Reductases, by Natalia Y. Kedishvili
Crystal Structure of Pig Heart Carbonyl Reductase, by Nobutada Tanaka, Ken-ichi Aoki, Shuhei Ishikura, Makoto Nagano, Yorishige Imamura, Akira Hara, and Kazuo T. Nakamura
Lead Optimization in the Design of Aldose Reductase Inhibitors, by Ganesaratnam K. Balendiran, Malkhey Verma, and Satish Bharadwaj
Selective Inhibitors of AKR1C3 as Anti-Proliferative Agents, by Michael C. Byrns and Trevor M. Penning
AKR1C1 and AKR1C3 as Potential Targets for Phytoestrogen Action, by Petra Brožič, Stanislav Gobec, and Tea Lanišnik Rižner
Searching for Inhibitors of Fungal 17β-Hydroxysteroid Dehydrogenase, by Katja Kristan, Matej Sova, Mojca Lunder, Tomaž Bratkovič, Stanislav Gobec, Borut Štrukelj, Jure Stojan, Jerzy Adamski, and Tea Lanišnik Rižner
Conversion of AKR1C20 into an AKR1C6-Type Enzyme by Site-Directed Mutagenesis, by Satoshi Endo, Toshiyuki Matsunaga, Kazuo Tajima, and Akira Hara
A Comparison of Methods for Assays of Steroidogenic Enzymes: New GC/MS versus HPLC and TLC, by Cornelia Prehn, Fabian Ströhle, Ferdinand Haller, Brigitte Keller, Martin Hrabě de Angelis, Jerzy Adamski, and Rebekka Mindnich
Purification of Aldo-keto Reductase AKR1B10 from Human Liver and Its Participation in the Carbonyl Reduction of Xenobiotics, by Hans-Jörg Martin, Ursula Breyer-Pfaff, Simone Block, Simone Venz, Vladimir Wsol, and Edmund Maser
Characterization of Guinea Pig Liver D-Xylulose Reductase of the Uronate Pathway: Identity with Sorbitol Dehydrogenase, by Shuhei Ishikura, Toshiyuki Matsunaga, Satoshi Endo, Kengo Matsumoto, Noriyuki Usami, Ossama El-Kabbani, and Akira Hara
Fungal Mannitol 2-Dehydrogenases and Mannitol-1-Phosphate 5-Dehydrogenases Constitute Novel Branches in the Protein Family of Polyol-Specific Long-Chain Dehydrogenases and Reductases, by Bernd Nidetzky and Mario Klimacek
Relative Efficacy of Aldo-keto Reductases in Catalyzing the Reduction of Phospholipid Aldehydes, by Matthew Spite, Oleg Barski, Yonis Ahmed, Aruni Bhatnagar, and Sanjay Srivastava
Δ4-3-Ketosteroid 5β-Reductase (AKR1D1): Properties and Role in Bile Acid Synthesis, by Jason E. Drury and Trevor Penning
Metabolism of 4-Hydroxy-trans-2-Nonenal (HNE)-Modified Proteins in Vascular Smooth Muscle Cells, by Bradford G. Hill, Sanjay Srivastava, Andrew Feldman, and Aruni Bhatnagar
Are 17β-HSDs Responsible for Increased Estradiol Concentrations within Ectopic and Cancerous Endometrium?, by Tina Šmuc, Katja Kristan, Gregor Bajc, Jasna Šinkovec, Martina Ribič-Pucelj, Bettina Husen, Hubert Thole, and Tea Lanišnik Rižner
Regulation of Promoter Activity of the Aldose Reductase Gene Through the Multiple Stress Response Region, MSRR, by Toru Nishinaka, Han Geuk Seo, Takeshi Miura, Tomoyuki Terada, and Chihiro Yabe-Nishimura
Expression of Carbonyl Reductases in Fetal Human Brain, but Not in Adult, by Hidetoshi Mizobuchi, Takeshi Miura, Kazutake Tsujikawa, Toru Nishinaka, and Tomoyuki Terada
Aldose Reductase Mediates Endotoxin-induced Cardiomyopathy and Septic Shock via Reduction of Lipid Aldehydes, by Kota V. Ramana, Monte S. Willis, Jureta W. Horton, Deepak Srivastava, Aruni Bhatnagar, and Satish K. Srivastava
Modulation of Gamma-Hydroxybutyrate Induced Sleep Using Hepatic AKR7A5 and AKR1A4 Inhibitors, by Elizabeth Litvinovich and Peter J. O’Brien
Aldose Reductase Inhibition Prevents Lipopolysaccharide-Induced NF-κB Signaling in Human Lens Epithelial Cells, by Aramati B. M. Reddy, Agnieszka Pladzyk, Umesh C. S. Yadav, Ravinder Tammali, Satish K. Srivastava, and Kota V. Ramana
Catalytic Activity of the β-Subunits of Voltage-sensitive Potassium Channels and Its Regulation by Pyridine Nucleotides, by Srinivas M. Tipparaju, Aruni Bhatnagar, and Oleg A. Barski
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